Incredible Footage Shows CRISPR Editing DNA in Real Time (ARTICLE LINK)


Excerpt
.....directly observing CRISR in action had never been done until now. Scientists know it works, because they get results, but the mechanism whereby it works has, until now, been essentially hypothetical. What is happening is simply too small for normal imaging methods.

To get around this problem, Nureki and his team used a technique called high-speed atomic force microscopy. An atomic force microscope consists of a very sharp-tipped probe on the free end of a cantilever. The probe lowers towards the surface and deflects away, over and over.

As it does this, a laser detects the slight changes of the deflections of the cantilever as it moves over raised surface features. These are recorded to create an image of what the probe is scanning.
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